Bleeding

CHICAGO — Three months of dual antiplatelet therapy after PCI may safely balance thrombosis and bleeding risk in both patients with low and high bleeding risk, compared with 1 and 12 months of DAPT, according to new data.

CHICAGO — Bentracimab, a recombinant human immunoglobulin G1 monoclonal antibody fragment, restored platelet function in patients on ticagrelor undergoing urgent surgery or with major bleeding, according to data from the REVERSE-IT trial.

Despite advances in anticoagulant therapies, bleeding remains a critical concern.

Midlife women with repeated episodes of heavy or prolonged menstrual bleeding over 6 months were 40% to 60% more likely to report feeling fatigued, underscoring the clinical importance of menstrual history during the menopause transition.

In January, Traumagel, a plant-based hemostatic gel that controls bleeding in seconds when applied to a wound at the point of care, saw its commercial release in the United States.

In a systematic review and meta-analysis of trials of non-vitamin K oral anticoagulants vs. single antiplatelet therapy, rivaroxaban was associated with higher rates of major bleeding compared with low-dose aspirin, researchers reported.

Reduced dosing of direct oral anticoagulants may offer comparable efficacy as full dosing for adults with venous thromboembolism history while decreasing bleeding risk and reducing health care utilization, according to study results.

Researchers identified various gaps in evaluation and management of heavy menstrual bleeding among a cohort of adolescents, according to study results presented at ASH Annual Meeting and Exposition.

PHILADELPHIA — The AIMS65 risk score may help predict which patients with direct oral anticoagulant-associated gastrointestinal bleeding are at heightened risk for rebleeding and death, according to late-breaking data.

PHILADELPHIA — Use of vasoconstrictors for up to 120 hours following endoscopic variceal ligation for acute variceal bleeding failed to demonstrate additional benefits vs. early discontinuation, according to data.