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Bipolar Disorder

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March 31, 2022
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Differences in neurodevelopmental maturation indicate higher risk for bipolar disorder

Differences in neurodevelopmental maturation indicate higher risk for bipolar disorder

Differences in neurodevelopmental maturation of structural brain networks leave certain adolescents at high genetic risk for bipolar disorder, according to an Australian study published in the American Journal of Psychiatry.

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March 09, 2022
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Serious mental illness tied to elevated CV risk; uncontrolled risk factors prevalent

Serious mental illness tied to elevated CV risk; uncontrolled risk factors prevalent

Individuals with serious mental illnesses such as bipolar disorder and schizophrenia may experience greater 10- and 30-year CV risk compared with those without a serious mental illness, researchers reported.

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February 22, 2022
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Sublingual dexmedetomidine reduces agitation in patients with bipolar disorder

Sublingual dexmedetomidine reduces agitation in patients with bipolar disorder

A sublingual film form of the selective alpha-2a-adrenergic receptor agonist dexmedetomidine significantly reduced mild to moderate agitation in patients with bipolar disorder, a phase 3 randomized trial showed.

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February 11, 2022
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Lybalvi for schizophrenia, bipolar disorder shows positive phase 3b results

Alkermes announced positive topline results from its phase 3b study of Lybalvi in young adults with schizophrenia, schizophreniform disorder or bipolar I disorder who were early in their illness.

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February 09, 2022
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Sunovion, Otsuka partner to study treatment for bipolar-linked major depressive episodes

Sunovion and Otsuka announced the first patient has been randomly assigned in their phase 3 clinical study of non-racemic amisulpride for treating major depressive episodes linked to bipolar I disorder.

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February 07, 2022
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‘Mental health is maternal health’: Screen, treat pregnant patients for bipolar disorder

‘Mental health is maternal health’: Screen, treat pregnant patients for bipolar disorder

Women should be screened and treated for bipolar disorder during pregnancy despite hesitations about pharmacologic treatment, according to a presentation at The Pregnancy Meeting.

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January 07, 2022
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Twins’ inheritance risk for mental illnesses greater in men than women

Likelihood of inheritance for hypomania, which may lead to bipolar disorder or other mental illnesses, is greater in male twins than in female twins, according to a Swedish cohort study published in JAMA Psychiatry.

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January 06, 2022
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Polygenic risk scores may be useful in finding bipolar disorder link in adults, offspring

Using polygenic risk scores to determine likelihood of parental bipolar disorder passing to offspring is promising but unproven, according to a community-based case-control longitudinal study published in JAMA Psychiatry.

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December 21, 2021
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FDA approves Caplyta for depressive episodes in bipolar I, II disorders

The FDA has approved Caplyta for treating adults with depressive episodes linked to bipolar I or II disorder, according to a company press release.

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November 17, 2021
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Lithium may not reduce suicide-related events in veterans with mood disorders

Lithium may not reduce suicide-related events in veterans with mood disorders

Adding lithium to usual care for veterans with major depression or bipolar disorders did not reduce incidence of suicide-related events, according to results of a randomized clinical trial published in JAMA Psychiatry.

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