Biomarker

Weight-tiered dose regimens of dupilumab affected type 2 biomarkers and kept dupilumab concentrations in a therapeutic range in children with moderate to severe asthma, according to a study.

For diagnosing systemic sclerosis-related ILD, Krebs von den Lungen-6, surfactant protein-D and interleukin-8 in blood/bronchoalveolar lavage fluid samples were found to be “reliable biomarkers,” according to results published in Thorax.

A composite biomarker index could improve the risk stratification and diagnosis of interstitial lung disease in patients with systemic sclerosis, according to data published in Arthritis & Rheumatology.

Data from four large studies with ancestry data show there are “clear differences” in associations between triglyceride levels with known cardiometabolic risk factors for people from West African, East African and European backgrounds.

A saliva-based test from Therapeutic Solutions International’s spin-off company Campbell Neurosciences successfully predicted suicidal ideation, according to a press release.

Healio spoke with Yasha Modi, MD, about biomarkers that can help predict a patient's risk for developing geographic atrophy.

Analyses of blood metabolite profiles showed that people with a history of mental illness had a biological age older than their actual age, according to a presentation at the European Congress of Psychiatry.

Patients with knee osteoarthritis demonstrated increased cartilage degradation and tissue turnover after a 3-month exercise-related joint loading training program, according to data published in Arthritis Research & Therapy.

In this video, Paul Nguyen, MD, a genitourinary radiation oncologist at Dana-Farber Cancer Institute, discusses the MMAI trial presented at ASCO Genitourinary Cancers Symposium.

A new blood test may be able to detect Alzheimer’s disease-related pathology up to 10 years before symptoms appear, according to a press release from Durin Technologies.