Biomarker

City of Hope announced two new key hires.

PSA level prior to salvage radiotherapy may be a prognostic biomarker for clinical outcomes of long-term antiandrogen therapy with salvage radiotherapy among men with prostate cancer, according to results of a secondary analysis of a randomized trial published in JAMA Oncology.

Use of voice signal analysis, an emerging noninvasive biomarker, may identify patients with congestive HF who are at highest risk for 20-month hospitalization or mortality, using voice analysis, according to research published in the Journal of the American Heart Association.

A blood test could determine whether children are sleeping enough, according to a study published in Experimental Physiology.

PHILADELPHIA — People at high risk for CVD, as assessed by risk factors, 10-year atherosclerotic CVD risk score and biomarkers, also have elevated risk for cancer, according to research presented at the American Heart Association Scientific Sessions.

NATIONAL HARBOR, Md. — Certain genetic biomarkers predicted long-term overall survival for patients who received adoptive cell therapy with tumor infiltrating lymphocytes for metastatic melanoma, according to the results of a multicenter, retrospective study presented at Society for Immunotherapy of Cancer Annual Meeting.

Researchers discovered a method to evaluate the cutaneous biomarkers of atopic dermatitis using minimally invasive tape strips, which may offer insight into tracking pediatric treatment responses in the future, in the top pediatric dermatology story at Healio.

Tumor mutational burden seems to have arrived at an uncertain juncture in its exploration as a potential biomarker for response to immunotherapy.

In a new analysis from the CANVAS trial, researchers identified 14 biomarkers with significant mediating effects on the efficacy of canagliflozin for HF among patients with type 2 diabetes, with erythrocyte concentration, serum urate and urinary albumin-to-creatinine ratio having the strongest effect.