Biomarker

Nathan A. Pennell, MD, PhD, spoke with Healio about a presentation focused on patients with EGFR-positive non-small cell lung cancer who have relapsed with osimertinib.

Gantenerumab decreased molecular markers of disease, but did not demonstrate a cognitive benefit, in patients with dominantly inherited Alzheimer’s disease, according to results from a phase 2/3 trial.

The Foundation for the NIH, in collaboration with the National Institute of Diabetes and Digestive and Kidney Diseases, announced a new partnership to investigate links across serious common diseases.

IACS-6274, a selective glutaminase-1 inhibitor, appeared safe and demonstrated antitumor activity among patients with biomarker-selected advanced solid tumors, according to phase 1 study results presented at the virtual ASCO Annual Meeting.

COVID-19 is predominantly considered an infectious and respiratory disease, but it is intertwined with the CV system as well. That means cardiologists have a lot to contribute to battle it, especially in the area of pathophysiology.

Genfit, in association with Labcorp, announced the launch of a noninvasive nonalcoholic steatohepatitis test for at-risk patients, according to a press release.

Serum Leucine-rich alpha-2 glycoprotein was a useful biomarker of endoscopic activity in patients with Crohn’s disease and ulcerative colitis taking Humira, according to a study published in Journal of Gastroenterology.

CV biomarkers that quantify myocardial injury, endothelial dysfunction, microvascular dysfunction and/or hemodynamic stress successfully provided modest discrimination in a noninvasive diagnosis of type 2 MI, researchers reported.

Lower brain glutamate levels were linked to antipsychotic exposure rather than to greater age-related decline in people with schizophrenia, according to results of a mega-analysis published in JAMA Psychiatry.

Fecal dipeptidyl peptidase-4 may be used as a noninvasive biomarker in patients with inflammatory bowel disease, according to research published in Clinical and Translational Gastroenterology.