Biomarker

Among Japanese outpatients with CV risk factors, the biomarker growth differentiation factor-15 was linked with increased risk for all-cause death and stroke events, researchers reported.

The use of in silico models is an effective method for identifying biomarkers of celiac disease, according to a presentation at the North American Society for Pediatric Gastroenterology, Hepatology & Nutrition Annual Meeting.

Urinary VEGF levels were lower in premature infants with severe lung disease who developed chronic kidney disease compared with those who did not develop CKD, implying VEGF may be a biomarker of CKD in this patient population.

Jeffrey A. Sparks, MD, MMSc, highlights a study from ACR Convergence 2021 that assessed biomarker predictors of rheumatoid arthritis-associated interstitial lung disease.

A risk model based on combinatorial messenger RNA and microRNA expression has potential clinical utility as a prognostic indicator of thyroid cancer recurrence, according to researchers.

A smartphone application may help clinicians detect concussion biomarkers, according to study results published in Life.

Use of a transforming growth factor-beta pathway-based combinatorial serum protein panel may aid in the early detection of hepatocellular carcinoma, according to research presented at The Liver Meeting Digital Experience.

An individualized, biomarker-guided approach to corticosteroid dosing utilizing C-reactive protein for COVID-19-related pneumonia reduced patients’ cumulative steroid exposure and increased the number of hospital- and oxygen-free days.

Despite an ever-growing array of potential candidate biomarkers for antineutrophil cytoplasmic antibody-associated vasculitis, it can be a long journey from “bench work” to bedside, according to a presenter at ACR Convergence 2021.

Plasma osteopontin levels are significantly higher in children hospitalized with moderate to severe COVID-19 and MIS-C than in those with mild or asymptomatic cases, suggesting a potential biomarker for disease severity, researchers said.