Biomarker

Xanthine oxidase and mitochondrial DNA damage-associated molecular patterns may represent novel biomarkers of resistant hypertension among Black patients, researchers reported.

SAN FRANCISCO — An artificial intelligence-derived digital pathology-based biomarker can help guide treatment decisions for men with localized intermediate-risk prostate cancer, according to study results presented at ASCO Genitourinary Cancers Symposium.

Germline microRNA-based biomarkers accurately predicted grade 2 or higher immune-related adverse events associated with anti-PD-1/PD-L1 therapy among patients with various cancer types, according to study results.

Molecules in saliva may be highly sensitive and specific noninvasive biomarkers of hepatocellular carcinoma, according to a study published in PeerJ.

Risk for heart failure with reduced ejection fraction due to elevated N-terminal pro-B-type natriuretic peptide levels is higher for women with early menopause compared with those without early menopause, according to study data.

Prognostic value of growth differentiation factor-15 for mortality in outpatients with CV risk factors.

The FDA has granted breakthrough device designation to Diadem U.S. Inc. for AlzoSure Predict, its blood-based test for early prediction of Alzheimer’s disease.

Neuroimaging company Imeka announced it has partnered with Atara Biotherapeutics Inc. to use Imeka’s novel biomarker technology in a phase 2 clinical study of individuals with progressive forms of MS.

Novel hepatitis B virus RNA and HBV core-related antigen blood assays revealed continued disease activity despite apparently suppressed virus replication among patients dosed with antiviral therapy for HBV and HIV coinfection.

NEW ORLEANS — Increased vimentin at the time of retinal detachment repair may help predict later development of proliferative vitreoretinopathy, according to a poster presentation at the American Academy of Ophthalmology meeting.