Barrett's Esophagus
Methylated DNA biomarker panel noninvasively detects esophageal cancer, precursors
A methylation biomarker panel paired with a minimally invasive sponge-capsule device identified Barrett’s esophagus, esophageal adenocarcinoma and high-grade dysplasia, according to a study published in American Journal of Gastroenterology.
The Next Generation of GI with Prateek Sharma, MD
In this podcast episode, Prateek Sharma, MD, about how program directors can help shepherd GI fellows into clinical research spaces, providing quality exams for upper endoscopy and more.
Obesity linked to higher risk for Barrett’s esophagus progression to dysplasia, cancer
Among patients with Barrett’s esophagus, every 5 kg/m2 increase in BMI was associated with up to a 6% relative increase in the risk for malignant progression, according to a systematic review and meta-analysis.
Prognostic tool may identify those with BE at higher risk for developing esophageal cancer
The biomarker-based Esopredict determined that patients with Barrett’s esophagus who were stratified as higher risk were 6.4-times more likely to progress to high-grade dysplasia or esophageal adenocarcinoma within 5 years, research showed.
Probability-based screening for BE, esophageal cancer could reduce screening needs by 45%
Targeted screening of older adults with GERD and a 5% probability of Barrett’s esophagus or esophageal adenocarcinoma could “substantially decrease” the population to screen, while still detecting more than 70% of disease, data showed.
AGA recommends endoscopic eradication vs. surveillance for BE with high-grade dysplasia
In a new clinical practice guideline, the AGA provides evidence-based recommendations for use of endoscopic eradication therapy in the management of Barrett’s esophagus, accounting for the presence of dysplasia and other scenarios.
‘Show your stripes:’ Rare Disease Day allows patients to share their stories, spread awareness
More than 300 million people worldwide, including one in every 10 Americans, are living with a rare disease, yet these individuals and their families are often left isolated and without answers.
World Trade Center firefighters using inhaled medication, steroids at risk for GERD
HONOLULU — Use of short-acting beta agonists and steroids each raised the likelihood for gastroesophageal reflux disease among firefighters exposed to 9/11 particulate matter, according to a presentation at the CHEST Annual Meeting.
Anti-reflux surgery for Barrett’s esophagus does not lower risk for esophageal cancer
Patients with Barrett’s esophagus who underwent anti-reflux surgery had an increased risk for esophageal adenocarcinoma over time compared with patients who used anti-reflux medication, according to research.
‘High burden’ of cancer worry in patients with BE, regardless of risk for progression
Patients with all stages of Barrett’s esophagus had similar cancer worry, highlighting the need for improved health-related quality of life through education, reassurance and follow-up care, according to data in BMJ Open Gastroenterology.