Autoimmune Disease
Checkpoint inhibitor response, adverse event rate similar regardless of autoimmune disease
Patients’ response to anti-CTLA-4 or anti-PD-1 checkpoint therapy for advanced melanoma, and their incidence of immune-related adverse events of grade 3 or higher, were similar regardless of preexisting autoimmune disease, according to data.
Diplopia and nystagmus present in patient with complex neuropsychiatric history
A 45-year-old woman was admitted to the neurology service at Lahey Hospital and Medical Center with symptoms of double vision, gait disturbance secondary to lower extremity weakness and subjective memory loss.
Patients with systemic autoimmune rheumatic diseases, COVID-19 at greater risk for VTE
Patients with systemic autoimmune rheumatic diseases and COVID-19 may be at greater risk for hospitalization, ICU admission, acute renal failure and venous thromboembolism, according to data published in Arthritis & Rheumatology.
Targeting immune checkpoints holds 'promise of more potent, refined' autoimmune therapies
Targeting immune checkpoints remains a key strategy in the development of treatments aimed at autoimmune disease and cancer, as well as for improving transplant outcomes, according to a review published in the Journal of Autoimmunity.
Getting to the heart of CV outcomes in rheumatic disease
CV events cause substantial morbidity and mortality among patients with rheumatologic diseases. Moreover, a robust body of data chronicles these associations.
Patients with rare autoimmune rheumatic disease more likely to die during COVID pandemic
The mortality risk for a 35-year-old patient with a rare autoimmune rheumatic disease during the COVID-19 pandemic is similar to that of a 55-year-old in the general population, according to UK data published in Rheumatology.
Multimorbidity 'highly prevalent,' progresses more rapidly in RA
Multimorbidity is highly prevalent, and progresses more rapidly, among patients with rheumatoid arthritis compared to those without the disease, according to data published in the Annals of the Rheumatic Diseases.
Vitamin D holds 'more unknowns than knowns' for autoimmune diseases
Vitamin D may be just one factor in the combination of “bad genes” and “bad luck” that causes autoimmune disease, according to a presenter at the 2020 Congress of Clinical Rheumatology-West.
Getting to the heart of cardiovascular outcomes in rheumatic disease
Cardiovascular events cause significant morbidity and mortality among patients with rheumatologic diseases. Moreover, there is a robust body of data chronicling these associations.
CVD risk reduction: How do you get this done?
There is a new addition to the Healio Rheumatology site that has allowed me to review all of my past editorials since our inaugural issue in November 2015. My first editorial topic was biosimilars, which sounds, well, so incredibly retro in the COVID-19 era.