Autoimmune And Rheumatic Diseases
Patients with prior sinusitis have greater rheumatic disease risk
Patients with prior sinusitis demonstrate an increased risk for many rheumatic diseases, including antiphospholipid syndrome, Sjögren’s disease and seronegative rheumatoid arthritis, according to data published in RMD Open.
VIDEO: Autoimmunity ‘surging’ in the general population
In this Healio video exclusive, Leonard Calabrese, DO, chief medical editor of Healio Rheumatology, breaks down top items from the March issue, including a roundtable on “surging” autoimmunity in the general population.
Autoimmunity, the exposome and the rise of integrative rheumatology
In this issue of Healio Rheumatology, we have a provocative roundtable on why there is provocative a rise in both autoimmune laboratory phenomenon, as well as an increase in certain autoimmune diseases over the past century.
Source of surging autoimmunity may lie in ‘a thousand cuts’
The common consensus for some time has been that the prevalence of autoimmunity and autoimmune diseases has been on the rise.
Medicare Part D spending at in-house pharmacies nearly quintupled from 2011 to 2019
Medicare Part D spending on prescriptions filled at in-house pharmacies nearly quintupled from 2011 and 2019, topping out at $1.6 billion, with increases concentrated among high-cost drugs, according to data published in JAMA Network Open.
FDA approves second tocilizumab biosimilar; first available in IV, subcutaneous forms
The FDA has approved Tyenne, the second tocilizumab biosimilar overall and the first available in both intravenous and subcutaneous formulations, according to a press release from its manufacturer.
Prolonged SARS-CoV-2 infections impact quarter of immunocompromised patients
Approximately 25% of patients with COVID-19 who are immunocompromised remain positive for the disease 21 days or more from initial onset, according to data published in The Lancet Microbe.
Patients with prior COVID-19 at higher risk for new-onset autoimmune inflammatory disease
Patients with a history of COVID-19 demonstrate a higher risk for new-onset autoimmune inflammatory rheumatic diseases, with greater infection severity linked to greater risk, according to data published in the Annals of Internal Medicine.
FDA approves Acthar Gel SelfJect injector in autoimmune, inflammatory conditions
The FDA has approved a supplemental new drug application for an Acthar Gel injector for the treatment of several chronic and acute inflammatory and autoimmune conditions, according to the manufacturer.
CAR T-cell therapy brings sustained, drug-free remission in three autoimmune diseases
Single injections of CD19 chimeric antigen receptor T-cell therapy brought long-lasting remission to 15 patients with three different autoimmune diseases, according to data published in The New England Journal of Medicine.