Autoantibody

On this episode, hear the 2024 updates on COVID-19, long COVID and the latest developments in research in rheumatology. Hosted by Dr. Leonard Calabrese.

A novel, fully automated multiparametric autoantibody analysis may improve the early diagnosis of connective tissue diseases, particularly lupus and Sjögren’s syndrome, according to data published in Arthritis Research & Therapy.

DESTIN, Fla. — Systemic lupus erythematosus may benefit from being redefined and further subdivided, depending on the autoantibody profile of the patient, according to a speaker at the Congress of Clinical Rheumatology East 2022.

Findings of minimal change disease in adults and children with autoantibodies targeting nephrin supports prior research demonstrated in animal models.

SARS-CoV-2 infection, even in asymptomatic cases, can lead to a broad autoantibody response that lasts beyond recovery from infection, according to findings published in the Journal of Translational Medicine.

Combined rheumatoid factor and anti-citrullinated protein antibody seropositivity was strongly associated with prevalent rheumatoid arthritis-associated interstitial lung disease in a cohort of U.S. veterans, researchers reported.

Children who have a relative with type 1 diabetes and a single islet autoantibody may be more likely to develop multiple autoantibodies if they have excess weight, according to findings published in Diabetes Care.

ATLANTA — Patients with juvenile dermatomyositis demonstrate obvious mitochondrial abnormalities in the tissue and periphery, supporting the use of anti-mitochondrial antibodies as a prognostic marker, according to data presented at ACR/ARP 2019.

Disease heterogeneity and the lack of a clear disease definition are among the top barriers to advancing lupus care, according to survey data published in Lupus Science & Medicine.