Atopic Dermatitis

The FDA has granted final approval for pimecrolimus cream 1%, a generic form of Elidel, according to an announcement from Glenmark Pharmaceuticals.

Baricitinib met the primary endpoint in adults with moderate to severe atopic dermatitis in BREEZE-AD7, the third pivotal phase 3 trial of the BREEZE-AD program, which is expected to be completed later this year.

According to research published in Trends in Microbiology, patients with atopic dermatitis, or AD, are commonly colonized with Staphylococcus aureus during flares. Bleach baths are one way clinicians are trying to reduce S. aureus colonization in AD patients and subsequently reduce disease severity.

Atopic dermatitis, one of the most common inflammatory skin conditions, begins in many patients by age 1 year, according to the American Academy of Dermatology. Globally, an estimated one in five children is affected by the disease. The prevalence is higher among children in developed countries, including the United States, and it may be increasing, researchers suggest.

Dupilumab showed consistent and sustained efficacy in an open-label extension study in adults previously enrolled in 12 parent studies assessing dupilumab in moderate to severe atopic dermatitis.

A resource on new developments in psoriasis in recognition of Psoriasis Action Month was the most popular story of the week at Healio Dermatology.

Children aged 6 to 11 years with severe atopic dermatitis assigned dupilumab and topical corticosteroids significantly improved in measures of overall disease severity, skin clearing, itching and health-related quality of life vs. topical corticosteroids alone in a phase 3 trial.

Variant frequency in the filaggrin gene was strongly associated with race among pediatric patients with atopic dermatitis.

NEW YORK — There are now multiple target treatments to utilize in patients with atopic dermatitis, but there is still a very large unmet need for better treatment in this disease, according to Emma Guttman-Yassky, MD, PhD, a Sol and Clara Kest professor of dermatology at Icahn School of Medicine at Mount Sinai in New York.

Dermatitis refers to various inflammations of the skin that occur in both children and adults. Some symptoms of dermatitis may overlap. The inflammation can be atopic, contact or seborrheic in nature but can also include mild conditions such as dandruff.