Atherosclerotic Cardiovascular Disease

A deep-learning model using information from a single chest X-ray reliably predicted atherosclerotic CVD risk and statin eligibility when compared with a common risk calculator, researchers reported.

CHICAGO — In this Healio video exclusive, Dipti Itchhaporia, MD, FACC, FESC, discusses some of the late-breaking science presented at the American Heart Association Scientific Sessions.

Lipoprotein(a) levels of 67 mg/dL or more may be indicative of similar risk for premature MI as LDL of 180 mg/dL or more in patients with familial hypercholesterolemia, researchers reported.

CHICAGO — In adults with atherosclerotic CVD or a risk equivalent, twice-yearly inclisiran injections were associated with a 44% reduction in LDL that was sustained over 4 years with no new safety signals observed, researchers reported.

CHICAGO — Olpasiran, a small interfering RNA agent directed to the liver, yielded substantial and sustained reductions in lipoprotein(a) concentrations among patients with established atherosclerotic CVD in the phase 2 OCEAN(a)-DOSE study.

LDL reduction is the major focus in the primary and secondary prevention of atherosclerotic CVD.

BOSTON — The medical community is better equipped to combat residual CVD risk than previously, but prevention of residual risk should be tailored using a precision medicine approach, a speaker said at the Cardiometabolic Health Congress.

BOSTON — There is strong evidence for a casual association between lipoprotein(a) concentration and CV outcomes across ethnicities, and Lp(a) “should be measured at least once” in all adults to identify high CV risk, according to a speaker.

The European Society of Cardiology Congress was held Aug. 26 to 29 in Barcelona, Spain, and online, having an in-person component for the first time since 2019.

An expert consensus decision pathway recently issued by the American College of Cardiology addresses lipid-lowering therapies that were developed after the publication of the ACC/American Heart Association cholesterol guidelines in 2018.