Atherosclerotic Cardiovascular Disease
Adults with high CAC score at similar risk for CV events as those with established ASCVD
Adults with a coronary artery calcium score greater than 300 are at an equivalent risk for major CV events as treated patients with established atherosclerotic CVD, supporting the use of high-dose statins in this population, data show.
In older patients with hardened arteries, women at greater risk for CV events vs. men
Among people aged 55 years or older who had a high burden of coronary atherosclerosis, women were at greater risk for a major adverse cardiovascular event than men, researchers reported.
During COVID-19 pandemic, some heart disease risk markers improved, but others worsened
Data show many people with atherosclerotic CVD did not have risk factors monitored during the COVID-19 pandemic, leading to variable outcomes in BP, lipid and glucose control, researchers reported.
Alirocumab improves coronary plaque burden in asymptomatic patients with FH
PCSK9 inhibition with alirocumab, on top of high-intensity statin therapy, resulted in significant coronary plaque regression among patients with familial hypercholesterolemia and no clinical atherosclerotic CVD, researchers reported.
REFERCHOL
Assessing odds for subclinical ASCVD by midlife based on maternal inheritance of FH.
Ertugliflozin reduces need for insulin with type 2 diabetes and atherosclerotic CVD
Adults with type 2 diabetes and atherosclerotic cardiovascular disease were less likely to need insulin and had a lower insulin dose requirement with 5 mg or 15 mg ertugliflozin daily compared with placebo, according to study data.
‘Potential cardiovascular risk’ for some on keto-style diet
NEW ORLEANS — Certain traditional risk factors including severe high cholesterol, diabetes, hypertension and smoking may increase CV risk among those following a low-carbohydrate, high-fat “keto-style diet,” a speaker reported here.
Menopausal hormone therapy safe for most women at low CVD risk
Menopausal hormone therapy for bothersome vasomotor or other symptoms is safe and appropriate for most women at low atherosclerotic CVD risk, whereas a nuanced approach is needed for intermediate-risk women, researchers reported.
ASCVD risk assessment practices miss opportunity to identify eligible young adults
Long-term prediction tools can further discriminate a subgroup of young adults with elevated atherosclerotic CVD risk as candidates for preventive therapy despite having low estimated short-term risk, researchers reported.
Healthy lifestyle can cut CVD risk in patients with FH
A healthy lifestyle was associated with reduced risk for CVD among adults with familial hypercholesterolemia regardless of their familial hypercholesterolemia mutation status, researchers reported.