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Atherosclerotic Cardiovascular Disease

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April 03, 2024
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Autoimmune blistering disorders associated with elevated cardiovascular risks, death

Autoimmune blistering disorders associated with elevated cardiovascular risks, death

Patients with autoimmune blistering disorders had elevated cardiovascular risks, including for atherosclerotic cardiovascular disease, heart failure, arrhythmia, venous thromboembolism and death, according to a study.

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March 26, 2024
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Chest X-ray AI analysis potentially predicts ASCVD risk for patients with missing EMR data

Chest X-ray AI analysis potentially predicts ASCVD risk for patients with missing EMR data

Artificial intelligence analysis of a single chest radiograph may predict 10-year CVD risk beyond the traditional atherosclerotic CVD risk calculator, even among individuals with missing electronic medical record data, researchers reported.

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March 06, 2024
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Many American Indian teens, young adults have dyslipidemia, elevated heart disease risk

Many American Indian teens, young adults have dyslipidemia, elevated heart disease risk

In a cohort of American Indian individuals, more than 70% of young adults and more than 50% of adolescents had dyslipidemia, and some had subclinical or clinical heart disease, according to new data from the Strong Heart Study.

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February 26, 2024
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High lipoprotein(a) linked to long-term risk for heart events, regardless of prior CVD

High lipoprotein(a) linked to long-term risk for heart events, regardless of prior CVD

In a real-world cohort, people with the highest levels of lipoprotein(a) had the greatest risk for long-term major adverse CV events, regardless of whether they had atherosclerotic CVD at baseline, researchers reported.

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February 17, 2024
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Why the cardiovascular community needs to take a closer look at inflammation

Why the cardiovascular community needs to take a closer look at inflammation

Heart disease continues to be the leading cause of death and disability in the U.S. and worldwide. Atherosclerotic CVD, which is caused by plaque buildup in arterial walls, contributes to multiple life-threatening conditions.

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December 14, 2023
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FDA approves expanded indications for bempedoic acid and combination tablet

FDA approves expanded indications for bempedoic acid and combination tablet

Esperion announced the FDA granted an updated indication for bempedoic acid and bempedoic acid plus ezetimibe for the treatment of primary hyperlipidemia in eligible patients with genetic hyperlipidemia or atherosclerotic CVD.

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December 14, 2023
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Use ‘more precise’ CVD risk scores to target therapy intensity for people with diabetes

Use ‘more precise’ CVD risk scores to target therapy intensity for people with diabetes

Composite CVD risk factor control for U.S. adults with type 2 diabetes remains poor, but clinicians can use newer risk scores to better assess patients and prevent CV events with targeted therapies, according to a speaker.

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December 12, 2023
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Removing race from heart disease risk calculator does not impact ASCVD prediction

Removing race from heart disease risk calculator does not impact ASCVD prediction

Modeling data suggest using race stratification in pooled cohort equation risk calculators does not change a person’s risk for developing atherosclerotic CVD, whereas adding social determinants of health did not improve model performance.

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December 01, 2023
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Black, Hispanic, Latino patients with ASCVD less likely to get optimal care

Black, Hispanic, Latino patients with ASCVD less likely to get optimal care

Despite population-wide improvements in use of lipid-lowering medication and cholesterol control since 1999, significant racial and ethnic disparities persist among patients with a history of atherosclerotic CVD, researchers reported.

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Bempedoic Acid Topic Review

Bempedoic acid (Nexletol, Esperion Therapeutics) is a nonstatin low-density lipoprotein cholesterol (LDL-C)-lowering drug.

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