Atherosclerotic Cardiovascular Disease

Atherosclerosis is a chronic, systemic, inflammatory and metabolic disease and pathologic process characterized by the accumulation of cholesterol and calcium plaque within the arterial wall. [Kobiyama K, et al. Circ Res. 2018;1a]

An acute coronary syndrome occurs when atherosclerotic coronary plaque becomes unstable, leading to a series of events eventually resulting in partial or total thrombotic occlusion of a coronary artery.

Ezetimibe is a nonstatin low-density lipoprotein cholesterol-lowering small molecule drug.