Appendicitis

Among children with suspected nonperforated appendicitis, antibiotic management appeared inferior to appendectomy, according to results of a large, noninferiority trial published in The Lancet.

A delayed diagnosis of appendicitis was associated with an increase in hospital care costs in a cohort of adults who underwent appendectomy, particularly among non-Hispanic Black patients, according to data in JAMA Network Open.

Postoperative antibiotic use did not improve rates of surgical site infection among pediatric patients with nonperforated appendicitis and gangrenous, suppurative or exudative findings, according to data in JAMA Surgery.

Preterm infants faced an increased risk for appendicitis in the first year of life, according to a study published in Pediatrics.

More than half of patients treated with antibiotics for acute appendicitis avoided surgery for up to 25 years, with researchers reporting no evidence of long-term risks with nonoperative management other than recurrence.

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Nonoperative management of acute uncomplicated appendicitis was associated with fewer complications in patients older than 65 years, while appendectomy was linked to reduced mortality, length of hospital stay and cost, regardless of age.

Non-Hispanic Black patients experienced higher rates of delayed appendicitis diagnosis and 30-day, postoperative hospital use compared with their white counterparts, according to research published in JAMA Surgery.

Non-Hispanic Black adults had higher rates of delayed appendicitis diagnoses in the ED compared with white adults, putting them at greater risk for perforated appendicitis and post-surgery infection, a recent study found.

Researchers have reported a link between increased incidence of appendicitis and warmer weather, independent of other environmental and behavioral factors, according to a study published in JAMA Network Open.