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March 05, 2025
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Antibiotics fall short of appendectomy for uncomplicated appendicitis in children

Antibiotics fall short of appendectomy for uncomplicated appendicitis in children

Among children with suspected nonperforated appendicitis, antibiotic management appeared inferior to appendectomy, according to results of a large, noninferiority trial published in The Lancet.

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June 25, 2024
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Eightfold higher odds for mortality with high-risk emergency GI surgery in older adults

Eightfold higher odds for mortality with high-risk emergency GI surgery in older adults

Although both patient frailty and type of procedure affected outcomes among adults older than 65 years undergoing emergency surgery, the level of procedure risk had a stronger link to adverse outcomes, according to researchers.

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May 09, 2024
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Patients with delayed diagnosis of appendicitis had 1.23-times higher hospital care costs

Patients with delayed diagnosis of appendicitis had 1.23-times higher hospital care costs

A delayed diagnosis of appendicitis was associated with an increase in hospital care costs in a cohort of adults who underwent appendectomy, particularly among non-Hispanic Black patients, according to data in JAMA Network Open.

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August 23, 2023
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Most patients treated with antibiotics for acute appendicitis do not experience recurrence

Most patients treated with antibiotics for acute appendicitis do not experience recurrence

More than half of patients treated with antibiotics for acute appendicitis avoided surgery for up to 25 years, with researchers reporting no evidence of long-term risks with nonoperative management other than recurrence.

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April 18, 2023
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Nonoperative management for appendicitis linked to fewer complications in older adults

Nonoperative management for appendicitis linked to fewer complications in older adults

Nonoperative management of acute uncomplicated appendicitis was associated with fewer complications in patients older than 65 years, while appendectomy was linked to reduced mortality, length of hospital stay and cost, regardless of age.

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February 07, 2023
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Black patients at higher risk for delayed diagnosis of appendicitis, increased readmission

Black patients at higher risk for delayed diagnosis of appendicitis, increased readmission

Non-Hispanic Black patients experienced higher rates of delayed appendicitis diagnosis and 30-day, postoperative hospital use compared with their white counterparts, according to research published in JAMA Surgery.

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August 24, 2022
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‘Antibiotics only’ effective alternative to appendectomy for uncomplicated appendicitis

‘Antibiotics only’ effective alternative to appendectomy for uncomplicated appendicitis

Nonoperative management of patients with acute, uncomplicated appendicitis is comparable to surgical treatment in safety and efficacy, although longer hospital stays and recurrence are possible, according to a meta-analysis in JAMA Surgery.

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July 15, 2022
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Top in GI: Outpatient appendicitis management; promising treatment candidate for NASH

Top in GI: Outpatient appendicitis management; promising treatment candidate for NASH

A recent study showed that outpatient antibiotic management was safe compared with in-hospital care for patients with acute appendicitis.

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July 08, 2022
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Outpatient antibiotic management safe for select adults with acute appendicitis

Outpatient antibiotic management safe for select adults with acute appendicitis

Outpatient antibiotic management was safe compared with in-hospital care, with no greater risk for complications or appendectomy, in a subgroup of patients with acute appendicitis, according to research.

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November 28, 2020
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Study: Antibiotics noninferior to appendectomy for appendicitis

Antibiotic treatment was noninferior to appendectomy for appendicitis, according to the results of a pragmatic, nonblinded, noninferiority, randomized trial published in The New England Journal of Medicine.

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