Aortic Regurgitation
Severe valvular disease, COVID-19 mortality ‘approaching’ 50% at 30 days
OVAL
UK TAVI: In real-world population, TAVR noninferior to surgery at 1 year
Low-risk TAVR for bicuspid valves yields few adverse events
Fluoroquinolones pose risk for aortic, mitral regurgitation
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Law of LaPlace Topic Review
The Law of LaPlace describes the factors that determine left ventricular wall stress, which is a major determinant of myocardial oxygen demand.
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Pulsus Bisferiens
Pulsus bisferiens occurs in patients with significant aortic valve regurgitation.
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Diastolic Murmurs
Diastolic murmurs include aortic and pulmonic regurgitation (early diastolic), and mitral or tricuspid stenosis (mid-late diastolic).
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Aortic Regurgitation
Aortic regurgitation occurs when blood flows retrograde (backwards) across the aortic valve from the aorta into the left ventricle during diastole.
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Afterload
Afterload is the hemodynamic parameter that reflects the force that the left ventricle has to overcome to eject blood through the aortic valve.