Antiretroviral Therapy
Two-drug dolutegravir regimen remains noninferior to three-drug regimen after 3 years
Financial incentives improve HIV viral suppression, retention in care
Financial incentives improved viral suppression and retention in care in adults beginning HIV treatment in Tanzania, according to results from a randomized controlled trial published in The Lancet HIV.
HIV not linked to COVID-19 risk, other highlights from AIDS 2020
W. David Hardy, MD, scientific and medical consultant, and adjunct professor of medicine in the division of infectious diseases at Johns Hopkins University School of Medicine, shared some important take-aways for clinicians from this year’s International AIDS Conference with Healio.
Blood donations by people taking drugs to treat, prevent HIV could be ‘cause for concern’
Blood donations from people on antiretroviral therapy to treat HIV or pre-exposure prophylaxis to prevent HIV infection could increase risk for HIV transfusion transmission if tests cannot detect the virus in the donations, study results showed.
Post-transplant cyclophosphamide expands donor options for alloBMT in patients with HIV
The use of post-transplant cyclophosphamide as graft-vs.-host prophylaxis can expand the donor pool to allow for haploidentical or mismatched donors for allogenic blood or marrow transplantation in patients with HIV, study findings showed.
Rapid ART initiative reduces time from diagnosis to viral suppression by half
The rollout of an ART optimization initiative in San Francisco decreased median time from diagnosis to virologic suppression by nearly half, according to findings in Clinical Infectious Diseases.
HIV incidence declines among men, women in Rakai, Uganda
The rate of HIV is decreasing quickly among women and men in Rakai, Uganda, due in part to the scale-up of voluntary medical male circumcision, or VMMC, and ART, according to findings presented during CROI.
Pomalidomide helps clear lesions caused by HPV infection
Low-dose pomalidomide was well-tolerated and helped clear high-grade squamous intraepithelial lesions caused by HPV in patients with and without HIV, according to research from the Conference on Retroviruses and Opportunistic Infections.
Early ART narrows life expectancy gap for people with HIV to zero
The gap in life expectancy between people with HIV and people without HIV has narrowed, and initiating ART early shortens it even further, giving people with HIV the same life expectancy as people without it, according to findings from CROI.
Triple-drug regimen yields favorable outcomes in drug-resistant TB
In a study conducted at three sites in South Africa, combination therapy with bedaquiline, pretomanid and linezolid led to favorable outcomes in most patients with highly drug-resistant tuberculosis.