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Antiretroviral Therapy

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March 19, 2024
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Top in ID: Cat-transmitted sporotrichosis; hybrid COVID-19 immunity

Sporotrichosis, a fungal infection being transmitted by feral cats, is a potential threat on the CDC’s radar.

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March 14, 2024
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‘Essential first step’: HIV study demonstrates potential of long-acting ART in Africa

DENVER — Long-acting ART was shown to be safe and effective in a study conducted in sub-Saharan Africa — an “essential first step” in demonstrating its potential use to treat HIV on the continent, an expert said.

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March 09, 2024
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VIDEO: People who struggle with daily HIV regimen should be offered long-acting injections

DENVER — People with HIV who have challenges adhering to a daily oral regimen should be offered long-acting formulations of ART, study findings suggest.

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March 06, 2024
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Investigational two-drug regimen safe, effective for patients with HIV

DENVER — Phase 2 study data showed that a once-weekly oral regimen of an investigational two-drug HIV treatment was well tolerated among patients with HIV and allowed them to maintain viral suppression.

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March 06, 2024
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VIDEO: IAS-USA endorses off-label use of long-acting ART for HIV

DENVER — The International Antiviral Society-USA (IAS-USA) has updated its HIV treatment guidelines to endorse the off-label use of long-acting injectable ART in patients with HIV viremia.

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February 27, 2024
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Long-acting ART for HIV effective for people who struggle with daily pills

Results from an ongoing trial showed that long-acting injectable ART for HIV is effective for people who struggle to consistently take a daily course of medication, the NIH and ViiV Healthcare announced.

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February 07, 2024
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Mortality among people with HIV on ART significantly declined from 1996 to 2020

Rates of cause-specific mortality among people with HIV on ART declined between 1996 and 2020, with the largest reductions being in rates of AIDS-related mortality, researchers found.

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November 14, 2023
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Pitavastatin lowers plaque volume, progression in lower-risk patients with HIV

PHILADELPHIA — Pitavastatin lowered noncalcified plaque volume and reduced risk for plaque progression compared with placebo in patients with HIV at low to moderate risk for CVD, according to new data from the REPRIEVE trial.

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October 26, 2023
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Obesity leads to suboptimal antiretroviral drug responses in people with HIV

Using physiologically based pharmacokinetic modeling combined with observed clinical data, researchers determined that obesity can lead to reduced exposure and response to antiretroviral drugs.

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August 01, 2023
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Long-acting ART, support services could increase HIV viral suppression, survival

Long-acting injectable cabotegravir/rilpivirine paired with extensive support services for nonsuppressed people with HIV with adherence barriers would likely increase viral suppression and improve survival, researchers found.

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