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Antihypertensive Agent

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November 17, 2024
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Dual-medication polypills effectively lowered blood pressure among South Asian adults

Dual-medication polypills effectively lowered blood pressure among South Asian adults

CHICAGO — Among adults living in India with elevated BP, three different dual-medication polypills containing combinations of recommended first-line antihypertensive agents effectively lowered ambulatory BP, researchers reported.

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August 05, 2024
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Top in cardiology: AHA calculator may reduce care eligibility; predicting atherosclerosis

Top in cardiology: AHA calculator may reduce care eligibility; predicting atherosclerosis

An estimated 16 million U.S. adults who qualified for statin and/or antihypertensive therapy would not be eligible for primary prevention under the American Heart Association’s new PREVENT risk calculator, researchers reported in JAMA.

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May 11, 2024
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Older women have higher probability of surviving to age 90 years with systolic BP control

Older women have higher probability of surviving to age 90 years with systolic BP control

Attaining systolic BP between 110 mm Hg and 130 mm Hg was associated with higher probability of surviving to 90 years of age among women aged 65 years and older, according to results of a real-world study published in Circulation.

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April 07, 2024
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Twice-yearly injectable antihypertensive drug lowers BP at 6 months: KARDIA-2

Twice-yearly injectable antihypertensive drug lowers BP at 6 months: KARDIA-2

ATLANTA — A single subcutaneous dose of zilebesiran, an investigational RNA interference agent, significantly reduced 24-hour mean ambulatory and office systolic BP at 6 months vs. placebo when added to other antihypertensive therapy.

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November 12, 2023
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Injectable antihypertensive drug lowers blood pressure for up to 6 months

Injectable antihypertensive drug lowers blood pressure for up to 6 months

PHILADELPHIA — Zilebesiran, an investigational subcutaneous RNA interference therapeutic, lowered systolic blood pressure at 3 months and sustained the reduction to 6 months, according to results of the phase 2 KARDIA-1 trial.

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November 03, 2023
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Sleep and hypertension: A two-way street of risks

Sleep and hypertension: A two-way street of risks

BOSTON — Data show sleep abnormalities are associated with hypertension; however, antihypertensive medications can in turn disrupt sleep, complicating treatment for patients, according to a speaker.

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April 26, 2023
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Polypills may be safe, effective for BP lowering vs. monotherapy, usual care or placebo

Polypills may be safe, effective for BP lowering vs. monotherapy, usual care or placebo

Compared with monotherapy, usual care or placebo, polypills containing three or four low-dose antihypertensive drugs were associated with greater achievement of target BP and more sustained BP lowering, according to a meta-analysis.

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April 11, 2023
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Effectiveness of common blood pressure drugs varies widely

Effectiveness of common blood pressure drugs varies widely

Blood pressure lowering with common antihypertension drugs varies widely among adults with hypertension, yet greater reductions are possible with personalized therapy, researchers reported.

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March 23, 2023
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CATIS-2

CATIS-2

Use of early vs. delayed antihypertensive treatment after onset of acute ischemic stroke to reduce risk for composite case-fatality and major disability at 3 months.

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February 14, 2023
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Delayed antihypertensive treatment may not affect outcomes of acute ischemic stroke

Delayed antihypertensive treatment may not affect outcomes of acute ischemic stroke

Researchers observed no difference in 3-month functional outcomes or mortality among patients with acute ischemic stroke who underwent early BP-lowering therapy compared with a delayed strategy, a speaker reported.

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