Antidepressants

Using etrasimod with opioids or antidepressants did not increase risk for serotonin syndrome-associated adverse events among patients with ulcerative colitis, according to a study published in United European Gastroenterology Journal.

Current use of antidepressants corresponded with faster cognitive decline in older adults with dementia, a cohort analysis published in BMC Medicine indicated.

Antidepressants were more effective than placebo in reducing anxiety symptoms among adults with moderate to severe generalized anxiety disorder, according to a review published in Cochrane Database of Systematic Reviews.

Nearly 50% of women who utilized antidepressant prescriptions before conception discontinued use after pregnancy without substitution of psychotherapy treatment, according to results of a cohort study published in JAMA Network Open.

FDA black box warnings about antidepressants for pediatric patients — meant to decrease suicidal thoughts and behavior — may have had the opposite effect, according to a systematic review.

Patients with COPD on antidepressants faced a heightened risk for pneumonia and exacerbations, according to results published in Thorax.

Clinical outcomes of commonly used antidepressants varied among older adults compared with sertraline, according to real-world study results conducted in Denmark and published in The American Journal of Psychiatry.

DALLAS — Initiation and continued use of certain antidepressants may cause more weight gain over 2 years, according to research presented at ObesityWeek.

Continuing adjunctive antidepressant therapy for 52 weeks after depressive episode remission in patients with bipolar 1 disorder did not significantly delay further mood episodes vs. stopping treatment after 8 weeks, according to a study.

An analysis of poisoning-related suicides in Australia identified several substances to be careful about prescribing, while finding that “many medicines are present at lower levels,” even in non-poisoning suicides.