Antidepressant

Among patients with cardiac disease, nearly 20% used psychotropic medications, and psychotropic medication use was linked to elevated risk for 1-year mortality, researchers reported.

The American Academy of Neurology has updated a guideline for treating painful diabetic neuropathy using oral and topical treatments.

Treatment-resistant depression prevalence varied by sex, race and age, according to results of a cross-sectional study published in Journal of Clinical Psychiatry.

Randomized clinical trials of antidepressants often contain placebo run-in periods despite their apparent lack of benefits to outcome, according to results of a systematic review and meta-analysis published in JAMA Psychiatry.

Anti-inflammatories and antidepressants may help prevent neurocognitive worsening among people with HIV, according to findings presented at the American Neurological Association annual meeting.

An implantable loop recorder feasibly and acceptably monitored arrythmias among patients taking psychotropic medication, according to results of a cohort study in a research letter published in JAMA Psychiatry.

Patients in primary care practices who “felt well enough” to stop certain antidepressants — and did so — were at higher risk for relapse of depression by 52 weeks compared with those who continued therapy, researchers wrote.

Recent data revealed an increase in medication use among nursing home residents in Ontario, Canada, “with the potential for adverse effects” during the COVID-19 pandemic, according to researchers.

A 4-week induction course of esketamine nasal spray may still benefit patients with treatment-resistant depression who did not exhibit a response in the first week of treatment.

Esmethadone, a once-daily pill for major depressive disorder, demonstrated rapid, robust and sustained antidepressant effects.