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Anticoagulant

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August 08, 2019
4 min read
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Anticoagulants may reduce VTE risk in children

Rivaroxaban and dabigatran reduced the risk for venous thromboembolism in children, according to three studies presented at the International Society on Thrombosis and Haemostasis Congress.

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June 11, 2019
2 min read
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Increasing vitamin K intake may stabilize anticoagulation in patients using warfarin

Increasing vitamin K intake may stabilize anticoagulation in patients using warfarin

Among patients with thromboembolic disease treated with warfarin, increased consumption of foods containing vitamin K may improve anticoagulant stability, according to findings presented at the American Society for Nutrition Annual Nutrition Science Meeting.

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May 10, 2019
16 min read
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Venous thromboembolism guidelines aim to clarify proper care in areas with ‘a lot of uncertainty’

Venous thromboembolism guidelines aim to clarify proper care in areas with ‘a lot of uncertainty’

Venous thromboembolism — which includes deep vein thrombosis and pulmonary embolism — causes up to 100,000 deaths annually in the United States and affects patients in numerous health care settings, regardless of age.

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Loeffler's Endocarditis

Loeffler’s endocarditis (a.k.a. Davies disease or endomyocardial fibrosis) occurs from any disorder that elevates the eosinophil count such as parasitic infections.

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CHADS 2 Score

The CHADS 2 score is a system used to predict the risk of thromboembolic stroke in patients with atrial fibrillation helping to guide to use of anticoagulation to prevent stroke.

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Warfarin

Warfarin is an anticoagulant that acts by inhibiting the enzyme that recycles vitamin K from its oxidized form resulting in active vitamin K depletion.

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Low Molecular Weight Heparin (LMWH)

Low molecular weight heparin (LMWH) is an anticoagulant injected subcutaneously or intravenously and acts via activation of antithrombin III which in turn inactivates thrombin and factor Xa to produce its effect.

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Bivalirudin

Bivalirudin (Angiomax) is a direct thrombin inhibitor used as an anticoagulant to treat acute coronary syndromes. Administration is intravenous only and it has a short half-life of 25 minutes.

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General Cardiology Pearls

Platypnea is shortness of breath that occurs when standing or sitting up and is relieved while laying supine (opposite of orthopnea).

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