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Anticoagulant

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January 21, 2022
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ACTIV-4A

ACTIV-4A

P2Y12 inhibitor plus anti-coagulation vs. anticoagulation alone in noncritically ill patients with COVID-19.

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January 14, 2022
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Frail patients less likely to receive certain blood thinners, despite recommendations

Frail patients less likely to receive certain blood thinners, despite recommendations

Among patients with nonvalvular atrial fibrillation, those with frailty were less likely to receive an anticoagulant and, if anticoagulated, were more likely to receive warfarin than a direct oral anticoagulant, researchers reported.

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January 11, 2022
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Shortened anticoagulation after provoked VTE safe, effective in young patients: Kids-DOTT

Shortened anticoagulation after provoked VTE safe, effective in young patients: Kids-DOTT

Among young patients with provoked venous thromboembolism, shorter duration of anticoagulation is noninferior to current standard of care, according to the results of the Kids-DOTT randomized trial.

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December 07, 2021
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Addition of P2Y12 inhibitor fails to benefit noncritically ill patients with COVID-19

Addition of P2Y12 inhibitor fails to benefit noncritically ill patients with COVID-19

In a cohort of noncritically ill patients with COVID-19, the addition of a P2Y12 inhibitor to anticoagulation did not extend survival or lessen disease severity, according to results of the ACTIV-4a trial.

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October 15, 2021
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More high-risk data needed on optimal antithrombotic therapy with TAVR

More high-risk data needed on optimal antithrombotic therapy with TAVR

Many patients undergoing transcatheter aortic valve replacement have multiple thrombotic and bleeding-related comorbidities that make optimal antiplatelet and anticoagulant management complex, leaving the question of which strategies are best open to debate.

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September 28, 2021
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Most patients on dialysis not prescribed anticoagulant after atrial fibrillation diagnosis

Most patients on dialysis not prescribed anticoagulant after atrial fibrillation diagnosis

A study assessing anticoagulant use in patients on hemodialysis who were diagnosed with atrial fibrillation revealed 81.5% did not initiate treatment with any anticoagulant within 30 days of being diagnosed.

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September 13, 2021
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Extended anticoagulant use for unprovoked VTE linked to ‘considerable’ bleeding risk

Extended anticoagulant use for unprovoked VTE linked to ‘considerable’ bleeding risk

Patients who continued to use anticoagulant therapy beyond the initial 3 to 6 months of treatment for a first unprovoked venous thromboembolism were at “considerable” risk for major bleeding, researchers wrote.

News
September 02, 2021
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For patients wtih atrial fibrillation, AKI risk lower with oral anticoagulant vs warfarin

For patients with atrial fibrillation, the risk for AKI was lower in those who were prescribed a direct oral anticoagulant than in those prescribed warfarin.

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August 17, 2021
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ACTION

ACTION

Rivaroxaban (Xarelto, Janssen/Bayer)-based therapeutic anticoagulation vs. standard of care in patients with COVID-19.

News
July 15, 2021
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Oral anticoagulants may lower bone density, trabecular bone score

Oral anticoagulants may lower bone density, trabecular bone score

Adults prescribed any oral anticoagulation therapy have lower bone mineral density and trabecular bone score compared with controls, with a stronger negative effect observed among those prescribed warfarin, data published in Bone show.

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