Antibiotic

Certain oral antibiotics are associated with increased risk for colon cancer, while others are linked with reduced rectal cancer risk, according to study results published in Gut.

An electronic medical record-driven antimicrobial stewardship program implemented in an Australian ICU was associated with high clinician compliance with recommendations and an improvement in the appropriateness of antibiotic prescriptions, researchers reported.

Researchers tested two core Infectious Diseases Society of America-recommended antimicrobial stewardship interventions at four community hospitals in North Carolina and found that one — post-prescription audit and review by a pharmacist after 72 hours of therapy — was feasible in facilities with limited resources and little to no antimicrobial stewardship expertise.

Antibiotics administered to treat Staphylococcus aureus appeared to inhibit disease activity among patients with advanced cutaneous T-cell lymphoma, according to results of a prospective study published in Blood.

Researchers found a dose-dependent association between antibiotic use in infancy and the development of asthma in childhood, regardless of the type of antibiotic administered or the timing of the prescription, according to study results published in Clinical Infectious Diseases. The researchers reported that the odds of future asthma diagnoses increased with each additional antibiotic prescription.

Physicians were more likely to receive a five-star satisfaction rating on a direct-to-consumer, or DTC, telemedicine platform when they prescribed antibiotics for pediatric respiratory tract infections, or RTIs. Researchers noted that pediatricians were less likely to prescribe antibiotics than other clinicians, yet had higher satisfaction ratings.

Findings from a systematic review and meta-analysis showed that more than 16% of patients who acquired antimicrobial-resistant bacteria, or ARB, did not have any antimicrobial exposure, researchers reported.

Children with complicated UTIs were safely and effectively treated with the combination antibiotic Avycaz compared with cefepime, according to findings from a phase 2 study published in The Pediatric Infectious Disease Journal.

Researchers estimated that approximately 23% of carbapenem resistant Enterobacteriaceae, or CRE, infections in the United States are treated with new anti-CRE antibiotics compared with about 28% of infections treated with IV polymyxins.

The antimicrobial market is broken and not everyone agrees on how to fix it.