Antibiotic

Antibiotic treatment was noninferior to appendectomy for appendicitis, according to the results of a pragmatic, nonblinded, noninferiority, randomized trial published in The New England Journal of Medicine.

Acute sinusitis is inflammation of mucosa lining of one or more paranasal sinuses. In children, most cases begin as a viral infection that extends from nasal mucosa (rhinitis) onto the mucosal lining of paranasal sinuses (sinusitis).

Although antimicrobial stewardship programs are well established in hospitals, they are not common in the outpatient setting, despite the fact that this is where the majority of antimicrobials are prescribed.

Patients with antibiotic allergy labels received more broad-spectrum antibiotics, had at least one negative outcome and accrued higher drug- or hospital-related costs, according to the results of a systematic review.

The clinical effectiveness of new antibiotics was similar compared with carbapenems for treating complicated UTIs, although the new treatments demonstrated a better microbiological response, researchers reported.

Data from more than 80 Veterans Affairs facilities showed a substantial increase in antibiotic use during the early months of the COVID-19 pandemic, rising to levels not seen since 2016, according to data presented at IDWeek.

Antibiotic prescribing in dozens of urgent care sites decreased after the introduction of a stewardship program, according to data presented at IDWeek.

With associated congruent reinfection and reoperation rates, oral antibiotics are noninferior to IV antibiotics for fracture-related infections, according to results presented at the Orthopaedic Trauma Association Annual Meeting.

Among children with community-associated pneumonia who have improved by day 5, study findings showed that additional days of antibiotic therapy did not confer additional benefits, researchers reported during IDWeek.

The overprescribing and overuse of antibiotics has been scrutinized in recent years due to the threat of antimicrobial resistance.