Antibiotic

Pediatricians often face the challenge of diagnostic accuracy in conjunctivitis cases. Compared with the common clinical syndromes of otitis media and pharyngitis, conjunctivitis presents less frequently and does not require systemic antibiotics. Nonetheless, not every single red or pink eye needs antibiotic drops.

Patients with drug-use-associated endocarditis are discharged with outpatient parenteral antibiotics less often than patients with non-drug-use-associated endocarditis, researchers reported.

A quality improvement program reduced antibiotic use and strengthened antimicrobial stewardship in hospitals, according to an analysis published in JAMA Network Open.

Reducing fluoroquinolone and piperacillin-tazobactam use may decrease resistance in nonfermenting bacteria, according to a recent study published in Open Forum Infectious Diseases.

Nearly half of women with uncomplicated UTIs received inappropriate antibiotics, and more than a quarter received treatment for an inappropriately long duration, according to a recent study.

Patients with low-risk methicillin-susceptible Staphylococcus aureus bacteremia who received short or prolonged antibiotic courses experienced similar mortality rates and clinical outcomes, according to a study.

Older adult patients who received antibiotic prophylaxis for UTIs experienced an increased risk for hospitalization, sepsis and bloodstream infection, according to a study in Clinical Infectious Diseases.

Maternal antibiotic use in the second and third trimester of pregnancy was associated with an increased risk for developing childhood asthma, according to research published in Archives of Diseases in Children.

Among adults with uncomplicated acute appendicitis, treatment with 7 days of oral moxifloxacin is not noninferior to a combination of IV and oral antibiotics, researchers reported.

High-risk patients who received extended antibiotics after total joint arthroplasty experienced a significant reduction in risk of periprosthetic joint infection, according to published and recently presented results.