Antibiotic

An assessment of 100 patients discharged from two medical short-stay units showed that 78% of their antibiotic prescriptions involved at least one type of antibiotic overuse, and 28% involved multiple types, researchers reported.

Use of antibiotics appeared consistently associated with higher subsequent risk for proximal colon cancer, according to results of a nationwide, population-based study published in Journal of the National Cancer Institute.

Although extended oral antibiotic treatment may reduce the rate of recurrent prosthetic joint infection following two-stage exchange, it may also increase drug resistance to the antibiotic used, according to results.

A study that assessed more than 22 million outpatient antibiotic prescriptions in the United States found that more than half were not associated with a clinician visit or an infection-related diagnosis, researchers reported.

Researchers retrospectively analyzed nearly 450,000 antimicrobial susceptibility test results from a couple dozen hospitals to identify antibiotic pairs with disjoint resistance.

Data from Veterans Health Administration pharmacies showed that outpatient antibiotic prescriptions declined by almost 4% annually from 2011 to 2018, researchers reported at the ECCMID virtual meeting.

There was a “strikingly high” level of antibiotic resistance among outpatient urine Escherichia coli isolates collected during a recent 9-year period in the United States, according to a study published in Clinical Infectious Diseases.

An intervention that was administered just before patients visited their family practitioner significantly reduced their expectations about receiving antibiotics for an upper respiratory tract infection, trial data show.

In patients with idiopathic pulmonary fibrosis, pirfenidone delayed new-onset respiratory adverse events and antibiotic prescriptions, but did not delay new prescription of concomitant antitussive drugs compared with placebo.

Fidaxomicin and vancomycin reduced shedding of Clostridioides difficile spores faster and were associated with lower rates of hospital contamination compared with metronidazole, according to study findings.