Antibiotic Therapy

Using a novel approach accounting for prescriber preference, researchers found that longer durations of antibiotic therapy was not associated with greater risk of harm or benefit compared to a shorter duration.

Physicians struggle to diagnose ear infections and often overprescribe antibiotics to children with acute otitis media, according to research published this year.

A 20-month outbreak of multidrug-resistant Enterobacter cloacae in an ICU was associated with the presence of cockroaches, according to a study that linked outbreak strains to strains found in the insects.

LOS ANGELES — Another study is suggesting that shorter is better — this time, a 2-week course of antibiotics for bloodstream infections was safely cut in half in a multinational randomized trial.

More than half of antibiotic prescriptions for acute sinusitis follow prescribing guidelines, but nearly one-third do not, and most prescriptions are given for too long a duration, according to a study.

Adults treated in EDs with established sepsis alert systems benefited from reduced mortality risk and length of hospitalization compared with facilities with no alert system, according to data published in JAMA Network Open.

Carbapenems were commonly prescribed as targeted therapy for extended-spectrum cephalosporin-resistant Enterobacterales infections despite significant changes in guidance, data show.

A 12-week course of suppressive antibiotic therapy for periprosthetic joint infections did not show an overall benefit, but it may be more effective among patients in the United States who have higher treatment failure rates, data show.

Despite suppressive antibiotic therapy being a routine strategy for managing periprosthetic joint infections, a study showed the benefits may be limited.