Antibiotic Prophylaxis

In children and adolescents with latent rheumatic heart disease, secondary antibiotic prophylaxis was associated with lower risk for disease progression at 2 years, researchers reported at the American Heart Association Scientific Sessions.

The 2007 decision to no longer advise antibiotic prophylaxis to prevent viridans group streptococcal infective endocarditis in many patients with CVD having invasive dental procedures was correct, according to a new scientific statement.

WAILEA, Hawaii — During the Hawaiian Eye complicated cataract case section here, Richard L. Lindstrom, MD, updated the audience on the fight to retain moxifloxacin as Category 1 for 503B outsourcing facility use.

Published results showed patients who were morbidly obese and received extended oral antibiotic prophylaxis after primary total hip or knee arthroplasty did not have reduced rates of wound complications or periprosthetic joint infection.

Older adult patients who received antibiotic prophylaxis for UTIs experienced an increased risk for hospitalization, sepsis and bloodstream infection, according to a study in Clinical Infectious Diseases.

Antibiotic stewardship may increase preferred prophylaxis and cefazolin use in patients with non-severe penicillin allergies who undergo total joint arthroplasty, according to recently presented results.

Only when quality evidence dictates it, should orthopedic surgeons change how they use antibiotics for prophylaxis and treatment after surgery, symposium participants said at the Musculoskeletal Infection Society Annual Meeting.

Extending oral antibiotics use to 7 days postoperatively in patients at high risk for prosthetic joint infection was effective at reducing infection rates, findings of a retrospective study of prospectively collected data showed.

A large study conducted at Aravind Eye Hospitals in India showed that intracameral antibiotic prophylaxis significantly reduced the risk for endophthalmitis after trabeculectomy with or without combined cataract surgery.

Debra A. Goff, PharmD, FCCP, recalled what inspired her and several colleagues to review guidelines on the use of antibiotics in dentistry for the prevention of endocarditis and prosthetic joint infections.