Antibiotic Prophylaxis

Postmenopausal women with vulvovaginal atrophy treated with intravaginal prasterone for at least 12 weeks were nearly 50% less likely to develop a urinary tract infection compared with untreated women, researchers reported in Menopause.

Antibiotics given during labor induction for women with obesity may cut cesarean delivery rates by up to 27%, likely by decreasing inflammation, data from a small pilot study suggest. Researchers now aim to learn more in an expanded trial.

Although rifaximin was well-tolerated in patients with severe cirrhosis and ascites, it did not improve transplant-free survival and cirrhosis-related complications and “cannot be recommended” as antibiotic prophylaxis, a researcher noted.

Experts say that the management of Q fever, a zoonotic disease caused by Coxiella burnetii, is complicated by the lack of clinical guidance on screening protocols, treatment regimens and durations.

Published results showed extended oral antibiotic prophylaxis was not associated with a reduced risk of periprosthetic joint infection at 90 days or 1 year among patients who underwent total hip or total knee arthroplasty.

Some common practices to prevent surgical site infections may not be necessary because no studies have shown benefits, according to a preconference presentation before ESCMID Global.

Initially recommended for use prior to dental procedures for patients with cardiac conditions to prevent infective endocarditis, the use of antibiotic prophylaxis has also increased to include a variety of patient populations.

CHICAGO — Addressing post-operative complications in the lower extremities can be a difficult task that needs nuanced care, according to a speaker at the American Society for Dermatologic Surgery annual meeting.

Adding vancomycin to cefazolin prophylaxis was not superior to placebo for the prevention of surgical-site infections among patients without known MRSA infection undergoing joint arthroplasty, researchers found.

Cefuroxime surgical antimicrobial prophylaxis should be administered within 60 minutes prior to incision to maximize risk reduction for surgical site infection in patients undergoing surgery, according to published results.