Ankylosing Spondylitis

Maternal ankylosing spondylitis is associated with a 2.02-times higher likelihood of Kawasaki disease in the offspring, according to a research letter published in JAMA Network Open.

Researchers found significantly lower treatment rates for women with ankylosing spondyloarthritis in multiple studies analyzing clinical trials in axial spondylarthritis, resulting in poor outcomes and response to therapies once started.

An 81-year-old man with significant medical comorbidities presented to the emergency room with neck and shoulder pain after a fall at a nursing home.

Healio Rheumatology compiled a list of the news in ankylosing spondylitis, including expert insight on pain management, drug updates and tips on diagnosis.

The European Commission has extended approval for AbbVie’s upadacitinib 15 mg to treat adult patients with active psoriatic arthritis and adult patients with active ankylosing spondylitis, according to a company press release.

Secukinumab demonstrated rapid, stained improvements in fatigue for up to 3 years among patients with ankylosing spondylitis, according to data published in Arthritis Care & Research.

Accurately diagnosing ankylosing spondylitis is a challenge for physicians, who must rely on a combination of symptoms and inflammation in place of a definitive blood marker.

Patients with ankylosing spondylitis demonstrated rapid clinical response to tofacitinib, which produced significantly greater efficacy than placebo, but with more adverse events, according to a speaker at ACR Convergence 2020.

Latent tuberculosis infection was an uncommon adverse event after treatment with secukinumab for chronic systemic inflammatory conditions, according to a study published in JAMA Dermatology.

TNF inhibitors and methotrexate produced similar reductions in HbA1c among patients with psoriatic arthritis, rheumatoid arthritis or ankylosing spondylitis who also have diabetes, according to data published in BMC Rheumatology.