Angle Closure Glaucoma

Eighteen medications appeared to be associated with angle-closure glaucoma, including sulfonamides, serotonergic agents and antimuscarinic agents, according to a retrospective analysis published in Ophthalmology Glaucoma.

A 58-year-old white woman with primary angle closure suspect was referred to the New England Eye Center glaucoma service for elevated IOP after bilateral laser peripheral iridotomy.

A 71-year-old woman was referred to the New England Eye Center for evaluation of elevated IOP in the left eye. Four weeks before presentation, she had undergone bilateral laser peripheral iridotomies due to concern for narrow angles. One week after the procedure, IOP in the left eye was elevated to 32 mm Hg, and an attempt was made to enlarge the peripheral iridotomy in the left eye at that time.

Earlier this year, The Lancet published the results of the LiGHT trial, comparing selective laser trabeculoplasty and eye drops to treat patients with open-angle glaucoma, which found SLT provided more robust IOP lowering while being a more cost-efficient first-line treatment.

Changes in IOP resulting from posture shifts were comparable among various forms of glaucoma, according to findings published in Optometry Vision and Science.

Glaucoma is traditionally characterized by progressive loss of the retinal ganglion cell layer, leading to visual field defects, advancing to central islands and, finally, total blindness. However, that may change in the future.

No additional benefit in IOP-lowering effect was seen when goniosynechialysis was added to phacoemulsification in patients with primary angle closure glaucoma and cataract.