Anaphylaxis

Some monoclonal antibodies used in the treatment of inadequately controlled severe asthma may pose anaphylactic risks, according to a retrospective study of post-marking surveillance data published in Clinical and Translational Allergy.

In a recent case series, researchers found that half of patients with a clinical allergy to sunflower seeds experienced anaphylaxis after undergoing allergy tests.

An animated video that was shown to children with a history of food-related anaphylaxis improved their understanding of anaphylaxis and how manage it, data show.

Anaphylaxis is often underdiagnosed and undertreated in children, but researchers at a busy tertiary care pediatric ED in Canada said they identified factors that predicted whether patients received epinephrine.

Anaphylaxis was rarely reported among the first 4 million recipients of the second COVID-19 vaccine authorized for use in the United States, the CDC and FDA reported in MMWR.

As of Dec. 23, there were 21 confirmed cases of anaphylaxis among the first 1,893,360 recipients of the Pfizer/BioNTech COVID-19 vaccine in the United States, the CDC and FDA reported in MMWR.

The American College of Allergy, Asthma and Immunology’s COVID-19 Task Force released guidance on allergic reaction risk from the Pfizer-BioNTech COVID-19 vaccine.

Researchers have developed an at-home anaphylaxis management algorithm for patients who need emergency epinephrine treatment. Importantly, it may prevent unnecessary ED visits — a particularly helpful development given the risk that COVID-19 poses in health care settings.

A new point-of-care clinical decision tool, PEN-FAST, may help identify patients with reported penicillin allergies who can safely undergo oral challenges and receive beta-lactam antibiotics without needing formal allergy testing, according to research published in JAMA Internal Medicine.

Although there have been improvements over the years, racial, socioeconomic and ethnic disparities in food allergy are still prevalent in the United States, according to a presentation at the American College of Asthma, Allergy & Immunology Scientific Meeting.