Amsterdam UMC
Low household income associated with increased risk for out-of-hospital cardiac arrest
A population-level study conducted by researchers in the Netherlands showed a significant association between household income and risk for out-of-hospital cardiac arrest.
Omicron breakthrough cases in patients with IMIDs on immunosuppressants ‘mild’
The incidence of omicron breakthrough cases of COVID-19 in patients with immune-mediated inflammatory diseases on immunosuppressants is high, but similar to controls, while disease severity is mild, according to data.
Most transgender adolescents continue to use gender-affirming hormones in adulthood
Most transgender adolescents who used pubertal blockers and were later prescribed gender-affirming hormone therapy in the Netherlands continued to use hormones as adults, according to data published in The Lancet Child & Adolescent Health.
GnRH analogue plus testosterone does not suppress adult height for transgender boys
Most transgender boys reach their predicted adult height after treatment with gonadotropin-releasing hormone analogues and testosterone therapy, according to data published in The Journal of Clinical Endocrinology & Metabolism.
Girls with type 1 diabetes may have worse cardiometabolic metrics than boys
Researchers observed sex disparities among children with type 1 diabetes, according to a presenter at the European Association for the Study of Diabetes annual meeting.
Third dose of COVID-19 vaccine effective for immunocompromised patients with blood cancers
A third dose of the mRNA-1273 vaccine for COVID-19 significantly improved SARS-CoV-2 antibody concentrations among patients with hematologic malignancies who previously received two doses, results of a prospective study showed.
Low-dose prednisolone beneficial in patients with established rheumatoid arthritis
Add-on low-dose prednisolone improves long-term disease activity and progression in senior patients with established rheumatoid arthritis, albeit with an increase in non-severe adverse events, according to data.
Neoadjuvant chemoradiotherapy extends OS vs. upfront surgery in pancreatic cancer subsets
Neoadjuvant gemcitabine-based chemoradiotherapy prolonged OS compared with upfront surgery among patients with resectable and borderline resectable pancreatic cancer, according to phase 3 study results in Journal of Clinical Oncology.
Third COVID vaccine dose raises seroconversion in patients receiving mycophenolate mofetil
Patients receiving mycophenolate mofetil combination therapies saw increased seroconversion after a third dose of SARS-CoV-2 vaccine, while patients on anti-CD20 and S1P modulators saw little impact from a third dose, researchers noted.
Quitting smoking yields CV benefit equivalent of three medications
The estimated lifetime treatment benefit of smoking cessation was comparable to the use of several pharmaceutical treatments combined, even when the analysis was limited to major CV events, researchers reported.