Amoxicillin
Order set cuts antibiotic use for pediatric ear infections in half
An electronic health record order set that preselected shorter antibiotic courses for acute otitis media cut antibiotic use for pediatric ear infections in half, according to findings presented at IDWeek.
Vonoprazan-bismuth triple therapy eradicates H. pylori in up to 90.9% vs. standard care
A triple therapy of vonoprazan, amoxicillin and bismuth potassium citrate achieved an eradication rate of just over 90%, similar to that of the standard quadruple therapy, in patients with Helicobacter pylori infection, according to data.
Treatment for H. pylori infection may yield ‘notable’ survival benefits in gastric cancer
Treatment for Helicobacter pylori was associated with improved overall and disease-free survival among patients with confirmed infection and gastric cancer who underwent gastrectomy, according to data published in JAMA Network Open.
Changes in prescription medication use by pregnant women after 2010 in US
Opioid and teratogenic medication prescriptions decreased and prescriptions for medications for diabetes and mental health conditions increased among pregnant women after 2010 in the U.S., researchers reported.
Amoxicillin remains effective against ear infections, small study shows
Amoxicillin remains effective against acute otitis media, according to the results of a small study published in the Journal of the Pediatric Infectious Diseases Society.
Short on amoxicillin, physicians reach for alternatives to treat ear infections
A national shortage of amoxicillin led to an increase in the use of alternative agents to treat ear infections, according to a study published in Pediatrics.
Prophylactic antibiotics do not reduce mortality in severe alcohol-related hepatitis
The use of amoxicillin-clavulanate with prednisolone did not improve 2-month survival compared with prednisolone alone in patients hospitalized with severe alcohol-related hepatitis, according to data in JAMA.
Pregnant women safely tolerate amoxicillin direct oral challenges
Pregnant women with a history of penicillin allergy safely passed direct oral challenges for amoxicillin without preceding skin testing, according to a study published in The Journal of Allergy and Clinical Immunology: In Practice.
Low-dose amoxicillin noninferior to higher dose for pediatric pneumonia
A lower dose of oral amoxicillin was noninferior to a higher dose in children with community-acquired pneumonia who were discharged from an ED or hospital ward, according to results of a 2x2 factorial, randomized clinical trial in JAMA.
‘Simple tool’ helps predict amoxicillin hypersensitivity
The PEN-FAST clinical decision tool can assist in efficient amoxicillin allergy assessment based on four recognizable features, according to a study published in Annals of Allergy, Asthma & Immunology.