Alzheimer's Disease

Treating high blood pressure later in life may mitigate risk for developing Alzheimer’s disease among older individuals, according to a meta-analysis published in Neurology.

PHILADELPHIA — A computerized cognitive battery was effective in detecting cognitive impairment and amyloid presence in preclinical Alzheimer’s disease, James E. Galvin, MD, MPH, said in this Healio Video Perspective.

PHILADELPHIA — In this Healio Video Perspective, Suzanne E. Schindler, MD, PhD, revealed phosphorylated tau biomarker assays were most accurate in identifying amyloid positron emission tomography status in Alzheimer’s disease.

PHILADELPHIA — An analysis of more than 15 million Americans enrolled in Medicare found that those enrolled in the Medicare Advantage plan had a 4% lower dementia diagnosis rate than those in traditional Medicare, according to a presenter.

Older adults with diabetes who spend less time within their individualized HbA1c target range have a higher risk for developing Alzheimer’s disease and dementias, according to findings published in JAMA Network Open.

Women with breast cancer who underwent hormone-modulating therapy exhibited a reduced risk for Alzheimer’s disease and related dementias, according to results of a retrospective cohort study.

PHILADELPHIA — Emergency medical service providers face challenges such as diagnosis, proper intervention and surrogate decision-making in treating critically ill individuals with dementia who require urgent medical intervention, according to a poster.

PHILADELPHIA — Treatment with lecanemab slowed the progression of a potential novel Alzheimer’s disease-related biomarker by 44% over 18 months compared with placebo, with the biomarker itself most correlating with tauopathy, data show.

PHILADELPHIA — Longer sleep duration may be linked to neurodegeneration as a likely risk factor for future cognitive decline and dementia, with depression also influencing sleep and cognitive deficit, according to a poster presentation.

PHILADELPHIA — Among men who played American football, researchers found that exposure to the sport at a younger age was strongly associated with worse cognitive performance and resilience, particularly in those who lived to at least 60 years.