Alzheimer's Disease
Small HDL particles in brain appear protective against Alzheimer’s disease
Small HDL particles play a significant role in the prevention of Alzheimer’s disease, and an inherited gene present in one in four people hinders its production in the brain, increasing risk for cognitive decline, a speaker reported.
Risk reduction strategies may improve cognition for older adults at risk for dementia
Modifiable risk reduction strategies improved cognitive scores as well as dementia risk factors and quality of life for older adults at risk for dementia, according to study results published in JAMA Internal Medicine.
Neighborhood disadvantage leads to poorer outcomes in those with focal epilepsy
ORLANDO — For a small cohort of individuals with focal epilepsy, “neighborhood disadvantage” was associated with poorer cognition including learning, memory and executive function, according to a poster.
Patent issued for ANAVEX2-73 in anxiety, insomnia
The U.S. Patent and Trademark Office has issued a patent expanding existing protections for ANAVEX2-73, a drug potentially effective in Alzheimer’s disease, according to a press release from the manufacturer.
Top in cardiology: New atrial fibrillation guideline; exercise and cardiovascular risk
The American College of Cardiology and the American Heart Association have updated their atrial fibrillation guideline to highlight early rhythm control and prevention strategies.
Phase 2 study of Alzheimer’s disease psychosis therapy initiated
A phase 2 clinical trial has been initiated to evaluate the safety and efficacy of an inverse agonist for hallucinations and delusions associated with Alzheimer’s disease psychosis, according to the manufacturer.
FDA clears platform for non-invasive brain chemistry measurement
The FDA has cleared the use of a magnetic resonance spectroscopy platform to provide non-invasive measurement of brain chemistry and support diagnostic processes for a range of brain-related illnesses.
Early-onset heart disease drives risk for Alzheimer's disease, other dementias
Adults with a diagnosis of coronary heart disease before age 45 years are 36% more likely to develop dementia over 13 years of follow-up compared with those without a CHD diagnosis, data from the UK Biobank show.
Food insecurity associated with dementia risk
Food insecurity was linked to an increased risk for dementia and faster memory decline among older adults, according to a study published in JAMA Network Open.
Visceral abdominal fat in midlife linked to Alzheimer’s disease
Having a higher amount of visceral abdominal fat in middle age was associated with an increased risk for developing Alzheimer’s disease, according to research presented at the annual meeting of the Radiological Society of North America.