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Alzheimer’S Disease Dementia

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September 11, 2024
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Trauma, sexual assault exposure may be ‘toxic’ for women’s brain health

Trauma, sexual assault exposure may be ‘toxic’ for women’s brain health

CHICAGO — Exposure to trauma was tied to increased measures of inflammation and neuronal death for Black women and accelerated brain age indicators regardless of race and ethnicity, researchers reported.

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August 29, 2024
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NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition

NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition

In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the rise and fall of VIOXX teach us about physiology?

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August 08, 2023
5 min read
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Q&A: Proposed changes to Alzheimer’s diagnostic criteria could be ‘game changer’ for PCPs

Q&A: Proposed changes to Alzheimer’s diagnostic criteria could be ‘game changer’ for PCPs

At the recent Alzheimer's Association International Conference in Amsterdam, an Alzheimer’s Association workgroup proposed revisions to the diagnostic criteria for Alzheimer’s disease.

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August 03, 2023
1 min read
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Vascular risk, younger age at menopause associated with cognitive decline

Vascular risk, younger age at menopause associated with cognitive decline

Early menopause and vascular processes may synergistically contribute to increased risk for Alzheimer’s disease in women, according to a poster presentation at the Alzheimer’s Association International Conference.

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March 22, 2023
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Noninvasive treatment improves cerebral blood flow, cognition in mild Alzheimer’s disease

Noninvasive treatment improves cerebral blood flow, cognition in mild Alzheimer’s disease

NEW ORLEANS — A device designed to improve cerebral blood flow with compression of lower limbs synchronized to the cardiac cycle was tied to improved cognitive performance scores in mild cognitive impairment or Alzheimer’s disease.

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February 21, 2023
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C₂N Diagnostics receives $15M to advance blood test for Alzheimer’s detection

C₂N Diagnostics receives $15M to advance blood test for Alzheimer’s detection

CN Diagnostics announced it has received a $15 million program-related investment from GHR Foundation to support and advance the PrecivityAD2 blood test for the detection of Alzheimer’s disease.

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February 07, 2023
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Oligomerix launches phase 1a trial for tau self-association inhibitor for Alzheimer’s

Oligomerix launches phase 1a trial for tau self-association inhibitor for Alzheimer’s

Dosing has begun in participants enrolled in a phase 1a clinical trial of OLX-07010, an oral small molecule inhibitor of tau self-association for Alzheimer’s disease, manufacturer Oligomerix announced in a press release.

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December 05, 2022
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Exercise stalled cognitive decline among adults with mild cognitive impairment

Exercise stalled cognitive decline among adults with mild cognitive impairment

Both moderate aerobic exercise and stretching and balance activities protected against cognitive decline in older adults with mild cognitive impairment, according to research at the Clinical Trials on Alzheimer’s Disease annual meeting.

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October 28, 2022
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Penn State awarded $1.2M grant for Alzheimer’s detection study

Penn State awarded $1.2M grant for Alzheimer’s detection study

A team of Penn State University researchers has been awarded a $1.2 million grant from the NIH to develop a machine learning system for the early detection of Alzheimer’s disease.

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September 20, 2022
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Phase 2 trial of therapeutic for patients with early AD yields positive results

Phase 2 trial of therapeutic for patients with early AD yields positive results

Alzheon Inc. reported statistically significant and clinically relevant results in patients with Alzheimer’s disease following 12 months of treatment with the oral investigational therapeutic ALZ-801 in its phase 2 trial.

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