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Alcohol-Associated Hepatitis

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November 15, 2021
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FMT restores gut barrier function, improves severe alcohol associated hepatitis outcomes

Improvements in intrahepatic and circulatory inflammation markers were observed after fecal microbiota transplantation in patients with severe alcohol associated hepatitis, according to a presenter at The Liver Meeting Digital Experience.

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November 15, 2021
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Lactobacillus therapy reduces heavy drinking in patients with alcohol associated hepatitis

A 6-month Lactobacillus rhamnosus GG treatment for moderate alcohol-associated hepatitis correlated with a decrease in heavy drinking levels to the social drinking or abstinence levels, according to a presentation.

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November 13, 2021
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Alcohol-associated hepatitis admission ‘dramatically’ increased in first year of COVID

There was an 81% increase in alcohol-associated hepatitis admissions within the first year of the COVID-19 pandemic and resulted in a significant increase in liver transplantation, according to a presentation.

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September 09, 2020
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VIDEO: ‘Promising’ treatment for alcoholic hepatitis in development

VIDEO: ‘Promising’ treatment for alcoholic hepatitis in development

In this exclusive video, Steven Flamm, MD, chief of the liver program at the Northwestern Feinberg School of Medicine, discusses a potential treatment for alcoholic hepatitis that is currently in development.

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August 28, 2020
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Genetic variant linked to reduced severe alcoholic hepatitis risk

People who carry a certain genetic variant are at lower risk for developing severe alcoholic hepatitis, according to research presented at The Digital International Liver Congress.

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August 28, 2020
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Virulence factors in gut determine mortality in alcoholic hepatitis

The carriage of virulence factors in the commensal gut microbiota was associated with mortality in patients with alcoholic hepatitis, according to research presented at The Digital International Liver Congress.

News
June 03, 2020
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Q&A: DUR-928 ‘well tolerated’ for NASH in Phase 1b study

Q&A: DUR-928 ‘well tolerated’ for NASH in Phase 1b study

Nonalcoholic steatohepatitis is a severe form of fatty liver disease that affects 3% to 5% of the population in the United States and currently no approved drugs are available for treatment, according to a press release from Durect Corporation.

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May 22, 2020
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Be aware of all factors related to HCC risk, not just HCV

Be aware of all factors related to HCC risk, not just HCV

Hepatitis C virus infection remains a strong driver of hepatocellular carcinoma with a high rate of progression to cirrhosis over an extended follow-up period, according to a study in International Journal of Molecular Sciences.

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February 27, 2020
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Call to action: Set new standards for alcohol-associated hepatitis transplant

Call to action: Set new standards for alcohol-associated hepatitis transplant

MAUI, Hawaii — To better manage alcohol-associated hepatitis, standards for the liver transplantation process should be altered as liver transplantation gains support as a therapeutic option for this disease, according to an expert at GUILD Conference 2020.

News
November 12, 2019
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VIDEO: Novel therapy safe, effective in acute, severe alcoholic hepatitis

VIDEO: Novel therapy safe, effective in acute, severe alcoholic hepatitis

BOSTON — In this exclusive video from The Liver Meeting 2019, Tarek Hassanein, MD, FAASLD, professor of medicine at UC San Diego Health and medical director of Southern California GI and Liver Centers, discusses results of a phase 2a study, which demonstrated that DUR-928 was well-tolerated and effective in patients with acute alcoholic hepatitis.

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