Adverse Drug Event

A novel GLP-1 and amylin receptor agonist featured a safety profile similar to other incretin-based therapies and conferred a significant weight reduction compared with placebo, according to top-line results from a phase 1b/2a trial.

The FDA has confirmed there is no longer a shortage of tirzepatide and has set dates for companies to cease distribution of compounded forms of the agent, according to an announcement from the agency.

The FDA is warning providers and patients that dosing errors with compounded injectable semaglutide may be leading to adverse events, according to a press release.

Otsuka has announced that a phase 3 clinical trial of AVP-786, a combination therapy to treat agitation associated with dementia due to Alzheimer’s disease, failed to achieve its primary endpoints.

Medication reconciliation is the process of creating the most accurate list possible of all medications a patient is taking and comparing that list against the physician’s orders at each transition of care.

Nipocalimab showed evidence of dose-dependent, statistically significant symptom reductions in patients with generalized myasthenia gravis, while remaining generally safe and well-tolerated, in a phase 2 trial.

HONOLULU — Treatment with nintedanib plus pirfenidone resulted in a similar frequency of adverse events as monotherapy among patients with idiopathic pulmonary fibrosis, according to a systemic review presented at the CHEST Annual Meeting.

New patients with rheumatoid arthritis are more likely to consider impact on physical function and the potential for adverse events when choosing therapy options, according to data published in BMC Rheumatology.

Hormonal treatments for hidradenitis suppurativa — particularly finasteride, spironolactone and metformin — are efficacious and safe for women, but dermatologists should be aware of treatment interactions, according to a review.

Although both are safe and effective, the Moderna COVID-19 vaccine was linked to greater protection and a slightly lower risk for adverse events compared with the Pfizer-BioNTech vaccine in older adults, data in JAMA Network Open show.