Adverse Childhood Experience
Higher dose of Spinraza improves motor function in infants with spinal muscular atrophy
Topline data from an ongoing clinical trial of a higher dose regimen of Spinraza in treatment-naive, symptomatic infants with spinal muscular atrophy showed significantly improved motor function at 6 months.
Adverse childhood experiences, resilience screening may ID pregnancy depression, anxiety
Routine screening for adverse childhood experiences and resilience may identify women at risk for developing depression or anxiety during pregnancy, according to a retrospective cohort study published in Obstetrics & Gynecology.
Depression mediates link between adverse childhood experiences, cognition in older women
Among midlife and older women in China, some of their own and their spouse’s adverse childhood experiences — mediated to some extent by depression — were associated with poorer cognitive function, according to study data.
Childhood sexual, emotional abuse increases multiple sclerosis risk in women
Women exposed to childhood sexual and emotional abuse had a greater risk for developing multiple sclerosis, according to a prospective cohort study published in the Journal of Neurology, Neurosurgery & Psychiatry.
Children who experience adverse childhood events may have worse chronic pain symptoms
Children with chronic pain or rheumatic disease who experience adverse childhood events may be at a greater risk for worse symptoms and “functional disability,” according to data published in Pediatric Rheumatology.
Lesbian, gay, bisexual, queer adults have high rates of adverse childhood experiences
Lesbian, gay, bisexual and queer people had higher exposure to all adverse childhood experiences compared with heterosexual adults, according to a cross-sectional study in a research letter published in JAMA Psychiatry.
Childhood trauma seen as ‘social determinant of health’ in neurology
Patients with neurological conditions had an increased risk for adverse childhood experiences compared with the overall U.S. population, according to results of a cross-sectional study published in Neurology: Clinical Practice.
Pandemic takes toll on mental health of older women with histories of trauma, violence
The COVID-19 pandemic may have had a greater impact on the mental health of older women with a history of childhood abuse or intimate partner violence than women without such histories, according to a study.
Negative experiences during early adolescence strongly linked to later adverse outcomes
Exposure to negative experiences during early adolescence was more strongly linked to later adverse outcomes vs. exposure at other points during childhood, according to study results published in JAMA Network Open.
Childhood abuse, neglect may significantly alter brain structure, function
Childhood abuse and neglect appear to have significant effects on brain structure and function, as well as on the epigenome, according to a presenter at the NEI Max virtual conference.