Adrenalectomy
Disease severity improves for most patients with primary aldosteronism after adrenalectomy
Adults with primary aldosteronism had improvements in disease severity after undergoing an adrenalectomy, according to findings published in Endocrine Practice.
Bone quality may improve after adrenalectomy for mild autonomous cortisol secretion
NEW ORLEANS —A small group of adults with mild autonomous cortisol secretion had an increase in spine trabecular bone score following adrenalectomy, according to a speaker at the AACE annual meeting.
Updated Cushing’s disease guideline highlights new diagnosis, treatment ‘roadmap’
An updated guideline for the treatment of Cushing’s disease focuses on new therapeutic options and an algorithm for screening and diagnosis, along with best practices for managing disease recurrence.
Black, Hispanic adults receive unequal treatment for adrenalectomy
Black and Hispanic adults undergoing adrenalectomy experience higher complication rates and longer hospital stay and have decreased access to high-volume surgeons compared with white counterparts, according to a database review.
Adequate timing key for biochemical evaluation after unilateral adrenalectomy
A biochemical evaluation to determine the success of unilateral adrenalectomy among adults with an aldosterone-producing adenoma should occur no sooner than 3 months after surgery, due in part to early postsurgical changes in active renin concentration, according to findings published in Clinical Endocrinology.
Basal plasma aldosterone predicts therapeutic outcomes in primary aldosteronism
Baseline plasma aldosterone concentration is independently associated with clinical and biochemical outcomes of treatment among adults with primary aldosteronism, and data suggest that mineralocorticoid receptor antagonist therapy is the optimal strategy vs. adrenalectomy for those with a normal plasma aldosterone concentration, according to findings published in the Journal of the Endocrine Society.
Five variables predict postoperative BP normalization in primary aldosteronism
A new predictive model based on Japanese registry data revealed several variables that can predict the normalization of blood pressure after adrenalectomy for primary aldosteronism, including hypertension duration, BMI, number of BP drug prescriptions, diabetes status and sex, according to findings published in the Journal of the Endocrine Society.
Cortical-sparing adrenalectomy reduces steroid replacement therapy in adrenal tumors
Adults with bilateral pheochromocytomas treated with cortical-sparing adrenalectomy were less likely to need steroid replacement therapy and had a low risk for tumor recurrence over 8 years when compared with similar patients who underwent total bilateral adrenalectomy, according to a retrospective database analysis published in JAMA Network Open.