Adrenal Gland

Adults with congenital adrenal hyperplasia receiving an oral corticotropin-releasing factor type 1 receptor antagonist had a greater reduction in daily glucocorticoid dose at 24 weeks than placebo, according to top-line phase 3 trial data.

Nearly one-third of women with endogenous Cushing’s syndrome and normal bone mineral density have a low trabecular bone score, according to study data.

Most adults with Cushing’s disease who received ketoconazole after transsphenoidal surgery had a reduction in cortisol to normal levels, according to findings published in Frontiers in Endocrinology.

CHICAGO—In this video exclusive, Maria Fleseriu, MD, FACE, and Adina Turcu, MD, MS, talk about research on adrenal disorders presented at ENDO 2023, including artificial intelligence and a debate about which patients to screen for primary aldosteronism.

In this video exclusive, Jonathan D. Leffert, MD, talks with Richard J. Auchus, MD, PhD, FACE, about how to define primary hyperaldosteronism, the importance of screening and tips for treating the disease.

Ambulatory fludrocortisone suppression testing for primary aldosteronism has similar accuracy compared with in-patient fludrocortisone suppression testing but with significantly lower health care costs, according to study data.

Adrenal gland volume is greater among adults with type 2 diabetes than without diabetes and might serve as a biomarker of metabolic status, according to study findings.

The use of an immunohistochemistry‒guided targeted amplicon sequencing approach using formalin-fixed, paraffin-embedded tissue detected somatic mutations in more than 70% of cortisol-producing adenomas, according to study data.

Black and Hispanic adults undergoing adrenalectomy experience higher complication rates and longer hospital stay and have decreased access to high-volume surgeons compared with white counterparts, according to a database review.