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Adjuvant Chemotherapy

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March 19, 2024
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VIDEO: No improvement in colon cancer ctDNA clearance after adjuvant chemotherapy

In this video, Afsaneh Barzi, MD, PhD, discussed the phase 2 results from the NRG-GI005 (COBRA) study.

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March 07, 2024
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Psychosocial, lifestyle-related factors affect breast cancer quality of life

Deteriorating quality of life for women with breast cancer was associated with many common modifiable psychosocial and lifestyle-related factors, according to an analysis published in JAMA Network Open.

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March 01, 2024
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Updated data ‘further supports’ adjuvant chemotherapy for upper tract urothelial cancer

Gemcitabine and platinum chemotherapy administered after nephroureterectomy SIGNIFICSALTY improved OS among certain patients with upper tract urothelial carcinoma, updated results form a randomized phase 3 study showed.

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January 25, 2024
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‘Disappointing’ results question the utility of liquid biopsy-guided cancer treatment

Circulating tumor DNA did not successfully predict whether patients with resected stage II colon cancer would benefit from adjuvant chemotherapy, according to findings presented at ASCO Gastrointestinal Cancers Symposium.

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January 25, 2024
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Circulating tumor DNA detection may predict treatment outcomes in colorectal cancer

Circulating tumor DNA-based detection of molecular residual disease appeared to be highly prognostic of patient outcomes, according to data presented at ASCO Gastrointestinal Cancers Symposium.

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November 08, 2023
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Race linked to quality, timeliness of care in adults with early-onset colorectal cancer

Black individuals with early-onset colorectal cancer received worse and less timely care compared with white patients, according to results of a national hospital-based study.

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June 20, 2023
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Pembrolizumab regimen fails to hit EFS target in gastric, gastroesophageal junction cancer

The addition of pembrolizumab to perioperative chemotherapy failed to significantly extend EFS among patients with locally advanced resectable gastric and gastroesophageal junction adenocarcinoma, according to the agent’s manufacturer.

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February 26, 2023
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Adjuvant chemotherapy extends survival in pancreatic cancer

Adjuvant chemotherapy appeared associated with a significant survival benefit among patients with pancreatic ductal adenocarcinoma who underwent multiagent neoadjuvant chemotherapy and resection, according to study results.

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June 08, 2022
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Adjuvant chemotherapy plus endocrine therapy fails to increase OS in breast cancer subset

CHICAGO — The addition of chemotherapy to endocrine therapy did not extend OS after surgery among older patients with ER-positive, HER2-negative breast cancer with a high tumor genomic grade index.

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December 01, 2021
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Premenopausal women may benefit from chemotherapy for node-positive breast cancer

Premenopausal women with node-positive breast cancer and low recurrence scores benefited from adjuvant chemotherapy, whereas postmenopausal women did not, according to results of a study published in The New England Journal of Medicine.

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