Adenocarcinoma

Having been exposed to benzene during work heightened the odds for lung cancer development, according to results published in American Journal of Respiratory and Critical Care Medicine.

A 75-year-old man presents for evaluation of profound fatigue of at least 3 months’ duration.

Progress in the non-endoscopic detection for Barrett’s esophagus may lead to increased identification of those at risk for esophageal adenocarcinoma, according to opinions published in Annals of Internal Medicine.

BARCELONA — Enriched cell surface expression of mesothelin in KRAS-mutated adenocarcinoma and supporting preclinical evidence suggest chimeric antigen receptor T-cell therapy targeting mesothelin may be feasible and efficacious for this group of patients, according to a presentation at International Association for the Study of Lung Cancer World Conference on Lung Cancer.

BARCELONA — One-third of health care professionals reported a lack of knowledge about evidence-based guidelines for molecular testing of lung cancer, according to survey results presented at International Association for the Study of Lung Cancer World Conference on Lung Cancer.

Patients with Barrett’s Esophagus with indefinite for dysplasia are at similar risk for malignant progression and should be screened like patients with low-grade dysplasia, according to results of a meta-analysis published in Gastrointestinal Endoscopy. “Currently, there are no reliable estimates for progression risk to [high-grade dysplasia/esophageal adenocarcinoma (HGD/EAC)] in patients with [Barrett’s esophagus with indefinite for dysplasia (BE-IND)],” Prasad G. Iyer, MD, MSc, from the division of gastroenterology and hepatology at Mayo Clinic in Rochester, Minnesota, and colleagues wrote. “Hence, management strategies for BE-IND are unclear and endoscopy is not routinely recommended.”