Acute Pain

NSAIDs “provide the greatest benefit and least harm” for treating acute pain in children compared with ketamine and opioids, according to findings from a systematic review and meta-analysis published in JAMA Pediatrics.

The FDA has often approved new drug applications for opioids based on trials of inadequate length that included only patients who could tolerate the drugs, according to researchers.

The FDA has approved Olinvyk — the first new IV chemical opioid agonist in decades — for adults with acute pain, the drug’s manufacturer announced.