Acute Lymphoblastic Leukemia

Invasive aspergillosis occurs in around 3% to 5% of children with acute leukemia, according to findings published in Journal of the Pediatric Infectious Diseases Society.

Use of blinatumomab with consolidation chemotherapy significantly extended OS for adults with minimal residual disease-negative B-cell precursor acute lymphoblastic leukemia, according to randomized phase 3 study results.

Children conceived via fresh or frozen embryo transfer may have increased risk for acute lymphoblastic leukemia compared with children conceived naturally, according to cohort study results published in JAMA Network Open.

Exclusive breastfeeding for at least 3 months was associated with reduced childhood hematologic cancer risk vs. shorter breastfeeding durations, according to cohort study results published in JAMA Network Open.

Patients with post-transplant relapsed B-cell acute lymphoblastic leukemia who received chimeric antigen receptor T-cell therapy had superior outcomes compared with alternative approaches, study results showed.

A COVID-19 diagnosis led to a delay in receiving chemotherapy among younger patients with acute lymphoblastic leukemia or lymphoblastic lymphoma, results from a retrospective analysis published in JAMA Network Open showed.

Benefits of chimeric antigen receptor T-cell therapy far outweigh the risks involved, including secondary T-cell malignancies, according to Peter Marks, MD, PhD, director of the FDA’s Center for Biologic Evaluation and Research.

Social determinants of health for children and young adults with leukemia and lymphoma must be researched as much as the diseases themselves to improve care, according to a presenter at ASH Annual Meeting and Exposition.

Ponatinib improved outcomes compared with imatinib for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia, according to study results presented at Society of Hematologic Oncology Annual Meeting.

Pediatric-inspired protocols and hyper-CVAD conferred comparable survival for adolescents and young adults with Philadelphia chromosome-negative acute lymphoblastic leukemia, according to study results.